Essay - Nephropathy Recent Searches for Information in Diabetic Nephropathy Yielded a...

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Recent searches for information in diabetic nephropathy yielded a limited amount of information concerning the disease, its diagnosis and its treatment. What was evident ***** ***** fact that it is another concern for those individuals who have been diagnosed w*****h diabetes, and further, that proper (and early) ***** can do much to stop the disease's progression and in many cases will prevent the disease.

Diabetic ***** presents itself in ***** with diabetes but it is closely related to nephrolithiasis which is a common condition that affects "n***** five perce*****t of U.S. men ***** women dur*****g *****ir lifetimes" FN1. Nephrolithias***** includes a number of different nephropathy diseases. "Nephrolithiasis specifically refers to calculi in the kidneys (including) both renal calculi ureteral calculi (ureterolithiasis)" FN2 Ureteral calculi almost always originate in ***** kidneys, although they may continue to grow once they lodge in the ureter. ***** is ********** referred ***** as kidney stones, ***** o*****r problems can occur pertaining to the ***** ***** two of the most prevalent conditions ***** to nephrolithiasis, which are IgA nephropathy and diabetic nephropathy.

According to the National Kidney and Urologic Diseases In*****mation Clearinghouse (NKUDIC) IgA nephropathy occurs "when IgA - a protein that helps us fight infections ***** settles in the kidneys" FN3.

***** nephropathy, on the other hand, occurs when there is too much protein and/or blood leaking from the kidney into the ***** stream. Many of the symptoms for both diseases are very similar.

Symptoms can include "swelling in the hands and feet, nausea, fatigue, headaches, and sleep problems" FN3.

Approximately 20 - 30 percent ***** individuals ***** diabetic nephropathy suffer kidney failure while 25 percent of IgA nephropathy sufferers will suffer ***** failure within 10 to ***** years of diagnosis. Nephrolithiasis produces a c*****lculi that can "be prevented in most patients by ***** use of a simplified evaluation, reasonable dietary and fluid recommendations, and directed pharmacologic intervention" FN1.

Dia*****tic nephropathy is normally referred to as diabetic kidney disease and it can lead to kidney *****. "Diabetic nephropathy presents in its earliest stage with low levels ***** album***** (microalbuminuria) in the ur*****e" FN4. Low levels of albumin ***** be detected by a number ***** methods with three of the most common being; a spot urine test, a 24-hour urine sample and a three to six month urine *****. "The ***** practical method of screening for microalbuminuria is to assess the albumin*****-creatinine ratio ***** a ***** urine test" FN4.

Once the diagnosis has been made early treatment can help to control ***** progress of the disease and ***** times will stave off kidney failure for a number of years. Thorp's study showed ***** "there is good evidence that early ***** delays or prevents the onset of diabetic nephropathy, or ***** kidney disease" *****. Early treatments can include a change in diet, exercise, improved blood sugar *****, pharmaceuticals and even a regime of vitamins.

A team of investigators ***** the journal Diabetes Care "demonstrated that ***** C and E, along with mineral supplementation (including magnesium) appear


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