Essay - Nephropathy Recent Searches for Information in Diabetic Nephropathy Yielded a...

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Recent searches for information in diabetic nephropathy yielded a limited amount of information concerning the disease, its diagnosis and its treatment. What was evident was the fact that it is another concern for those individuals who have been diagnosed w*****h diabetes, and further, that proper (and early) treatment can do much to stop the disease's progression and in many cases will prevent the disease.

***** nephropathy presents itself in *****dividuals with diabetes but it is closely related to nephrolithias***** which is a common condition that affects "n***** five percent of U.S. men and women during *****ir lifetimes" FN1. Nephrolithiasis includes a number of different nephrop*****thy diseases. "***** specifically refers to calculi in the kidneys (including) both renal ***** ureteral calculi (ureterolithiasis)" FN2 Ureteral calculi almost always originate in the kidneys, although they may continue to grow once they lodge in the ureter. Nephrolithiasis is *****ly referred ***** as kidney stones, but other problems ***** occur pertaining to the ***** including two ***** the most prevalent conditions related ***** nephrolithiasis, which are IgA nephropathy and diabetic nephropathy.

According to ***** National Kidney and Urologic Diseases In*****mation Clearinghouse (NKUDIC) IgA nephropathy occurs "when IgA - a protein ***** helps us fight infections - settles in the kidneys" FN3.

Diabetic *****, on the other hand, occurs ***** there is too much ***** and/or blood leak*****g from the kidney into the ***** stream. Many of the symptoms for both diseases ***** very similar.

Symptoms can include "swelling in the hands and feet, nausea, fatigue, headaches, and sleep problems" FN3.

Approximately 20 - 30 percent of individuals ***** diabetic nephropathy suffer kidney failure while 25 percent ***** IgA ***** sufferers will suffer kidney failure within 10 to ***** years of diagnosis. ***** produces a c*****lculi that can "be prevented in most patients by ***** use of a simplified evaluation, reasonable dietary and fluid recommendations, and directed pharmacologic *****tervention" FN1.

Dia*****tic nephropathy is normally referred to as diabetic kidney dise*****e and it can lead to ***** *****. "Diabetic nephropathy presents in its earliest stage with low levels ***** albumin (microalbuminuria) in the ur*****e" FN4. Low ***** of albumin can be detected by a number ***** methods with three of the most common being; ***** spot urine test, a 24-hour urine sample ***** a three to six month urine s*****mple. "The most practical method of screening for microalbuminuria is to assess the albumin*****-creatinine ratio with a spot urine *****" FN4.

Once the diagnosis has been made early treatment ***** help to control the progress of the disease and ***** times will stave off kidney fail***** for a number of years. Thorp's study showed ***** "***** is good evidence that early treatment delays or prevents ***** onset of diabetic *****, or diabetic ***** disease" *****. Early treatments can include a change in diet, exercise, improved blood sugar control, pharmaceuticals ***** even a regime of vitamins.

A team of investigators ***** the journal Diabetes Care "demonstrated that vitamins C and E, along with mineral supplementation (including magnesium) appear


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