Essay - Severe Acute Respiratory Syndrome Thesis Sars Epidemic Created a Medical...

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Severe Acute Respiratory Syndrome


SARS epidemic created a medical emergency and a healthcare crisis with the loss of hundreds of lives in a short sp*****n of time. The knowledge of the etiology of ***** disease ***** the genome sequence of the virus provided new impetus in treatment of ***** disease. The crisis was successfully managed through an international cooperative effort and today we are better prepared to handle possible future outbreaks of the epidemic.


SARS is an acute infectious respiratory d*****ease ***** all ***** symptoms of atypical pneumonia like fever, breathlessness that caused severe casualties in a short period of time. The first *****stance ***** SARS infection ***** reported in November 2002 in the Guangdong province of china. The SARS epidemic created a panic worldover and the World Health Organization issued a global alert on March 12th 2003 about the rapid spread of symptoms of atypical *****. Symptoms of ***** pneumonia ********** reported in China ***** Hong Kong in February and ***** of ***** and ***** created panic at the global level with 774 deaths and more than 8000 infected people. China, Taipei, Canada ***** Hong Kong suffered ***** most from the epidemic while sporadic SARS infections were found in many European nations and North America. Hundreds of people exhibiting ***** were quarantined ***** treated for ***** complications until the ***** outbreak was fully contained. In July 2003 China ********** announced ***** successful ***** of the last 12 cases of SARS. The present problem however is ***** early detection ***** the virus as the currently available diagnostic tools are ei*****r time consuming (ELISA and Immunofluorescence) or highly sensitive without any conclusive detection. (PCR). A discussion of the epidemiology, transmission, and the latest research results ***** treatment methods would provide a better underst*****nding of the disease.

***** S*****RS Virus

Ever since the ***** of the epidemic in February ***** lab*****atories worldwide ***** ********** in research to hasten ***** identification of the agent ***** was responsible for ***** symptoms of atypical pneumonia. The World health organization instituted a combined rese*****rch by eleven laboratories on March 17th to speedup the research, as by then, the ***** was starting to take its toll. By the end of March *****ers in ***** K*****g ***** to f*****d out traces of a novel coronavirus in the affected patients. ***** means ***** cell culture, electron microscopy and immuno-fluroscent antibody tests researchers in United States and Germ***** also confirmed the existence of a speci*****l type of coronavirus. Coronavirueses have the largest genome size ranging from 27 kb to 32 ***** and ***** been well known to cause ***** disorders in animals. Coronoviruses are easily transmitted by way of droplets, touch and small particulates in the air. They also have very ***** incubation periods as is the case with the SARS virus which has an incubation period between 2 and 7 days. On April *****th 2003 scientists working at ***** Michael Smith Genome Sciences center suces***** mapped out the genetic sequence of the SARS virus making way for


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