Essay - Severe Acute Respiratory Syndrome Thesis Sars Epidemic Created a Medical...

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Severe Acute Respiratory Syndrome


SARS epidemic created a medical emergency and a healthcare crisis with the loss of hundreds of lives in a short sp*****n of time. The knowledge of the etiology of the disease ***** the genome sequence ***** the virus provided new impetus in treatment of the *****. The crisis was successfully managed through an international cooperative effort *****d today we are better prepared to handle possible future outbreaks of the epidemic.


SARS is an acute infectious respiratory d*****ease with all ***** symptoms of atypical pneumonia like fever, breathlessness that caused severe casualties in a short period of time. ***** first instance of SARS infection ***** reported in November 2002 ***** the Guangdong province of china. The SARS epidemic ***** a panic worldover and the World Health Organization issued a global alert on March 12th 2003 about the rapid spread of symptoms of atypical *****. Symptoms of ***** pneumonia *****re reported in China ***** Hong Kong in February and ***** of 2003 and ***** created panic at ***** global level with 774 deaths and more than 8000 infected people. China, Taipei, Canada ***** Hong ***** suffered the most from the epidemic while sporadic SARS infections were found in many European nations and North America. Hundreds of people exhibit*****g ***** ***** quarantined ***** treated for ***** complications until the ***** outbreak was fully contained. In July ***** ***** *****ficially announced the successful ***** of the last 12 cases of SARS. The present problem however is the early detection of the virus as the currently available diagnostic tools are either time consuming (ELISA and Immun*****luorescence) or highly sensitive without any conclusive detection. (PCR). A discussion of the epidemiology, transmission, and the latest research results and treatment methods would provide a ***** underst*****nding of the disease.

The SARS Virus

Ever since the ***** of the epidemic in ***** 2003 laboratories worldwide were involved in research to hasten the identification of the agent ***** was responsible ***** ***** symptoms of atypical pneumonia. The ***** health organization instituted a combined ***** by eleven l*****boratories on March 17th to speedup the research, as by then, the ***** was starting to take its toll. By the end ***** March researchers in ***** Kong ***** to f*****d out traces of a novel coronavirus in the affected patients. By means of cell culture, electron microscopy and immuno-fluroscent antibody tests researchers in United States and Germ***** also confirmed the existence of a special type of coronavirus. Coronavirueses have the largest genome size ranging from 27 kb to 32 kb and have been well known to cause respiratory disorders in animals. Coronoviruses are easily transmitted by way of droplets, touch ***** small particulates in the air. They also have very ***** incubation periods as is the case with the SARS virus which has an incubation period between 2 and 7 days. On April *****th 2003 scientists working at the Michael Smith Genome Sciences center suces***** mapped out ***** genetic sequence of the SARS ***** making way for


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