Essay - Severe Acute Respiratory Syndrome Thesis Sars Epidemic Created a Medical...


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Severe Acute Respiratory Syndrome

Thesis

***** epidemic created a medical emergency and a healthcare crisis with the loss of hundreds of lives in a short span of time. The knowledge of the etiology of the disease and the genome sequence ***** the virus provided new impetus in treatment of the disease. The crisis was successfully managed through an international cooperative effort and today we are better prepared to h*****le possible future outbreaks of ***** epidemic.

Introduction

SARS is an acute infectious respira*****ry d*****ease with all the symptoms of atypical pneumonia like fever, breathlessness that caused severe casualties in a short period ***** *****. ***** first instance of SARS infection was reported in November 2002 in the Guangdong province of china. The SARS epidemic ***** a panic worldover and the World Health Organization issued a global alert on March 12th 2003 about the rapid spread of symptoms of atypical pneumonia. Symptoms of ***** pneumonia were reported in China ***** Hong Kong in February and March of 2003 and ***** created panic at the global level ***** 774 deaths and more than 8000 infected people. China, Taipei, Canada and Hong Kong suffered ***** most from the epidemic while sporadic SARS infections ***** found in many European nations and North America. Hundreds of people exhibiting symptoms were quarantined and treated for ***** complications until the SARS outbreak was fully contained. In July ***** China ********** announced the successful ***** of the last 12 cases of SARS. The present problem however is ***** early detection of the virus as the currently available diagnostic tools are either time consuming (ELISA and Immunofluorescence) or highly sensitive without any conclusive detection. (PCR). A d*****cussion of the epidemiology, transmission, ***** the latest research results and treatment methods would provide a better understanding of the disease.

***** S*****RS Virus

Ever since ***** spread of the epidemic in February 2003 laboratories worldwide ***** involved in research to hasten ***** identification of the agent that was responsible for ***** symptoms of atypical pneumonia. The ***** health organization instituted a combined ***** by eleven laboratories on ***** 17th to speedup the research, as by then, the virus was starting to take its *****ll. By ***** end ***** March researchers in ***** Kong ***** to find out traces of a novel coronavirus in the affected patients. ***** means of cell culture, electron microscopy and immuno-fluroscent antibody tests researchers in United States and Germany also confirmed the existence ***** a special type of coronavirus. Coronavirueses have the largest genome size rang*****g from 27 kb ***** 32 ***** and ***** been well known to cause respiratory disorders in animals. Coronoviruses are easily transmitted by way of droplets, touch and small particulates in the air. They also have very short incubation periods as is the case with the SARS virus which has an incubation period between 2 ***** 7 days. On April *****th 2003 scient*****ts working at ***** Michael Smith Genome Sciences center suces***** mapped out the genetic ***** of the SARS virus making way for

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