Essay - Severe Acute Respiratory Syndrome Thesis Sars Epidemic Created a Medical...


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Severe Acute Respiratory Syndrome

Thesis

***** epidemic created a medical emergency and a healthcare crisis with the loss of hundreds of lives in a short sp*****n of time. The knowledge of the etiology of ***** disease and the genome sequence of ***** virus provided new impetus in treatment of the *****. The crisis was successfully managed through an international cooperative effort and today we are better prepared to handle possible future outbreaks of the epidemic.

Introduction

SARS is an acute infectious respiratory d*****ease ***** all the symptoms of atypical pneumonia like fever, breathlessness that caused severe casualties in a short period of *****. The first *****stance ***** SARS infection was reported in November 2002 ***** ***** Guangdong province of china. The SARS epidemic ***** a panic worldover and the World Health Organization issued a global alert on March 12th 2003 about the rapid spread of symptoms of atypical *****. Symptoms of atypical pneumonia were reported in China and Hong Kong in February ***** March of ***** and SARS created ***** at ***** global level with 774 deaths and more than 8000 infected people. China, Taipei, Canada and Hong ***** suffered the most from the epidemic while sporadic ***** infections ***** found in many European nations and North America. Hundreds of people exhibiting ***** were quarantined ***** treated for the complications until the SARS outbreak was fully contained. In July 2003 China officially announced ***** successful ***** of the last 12 cases of SARS. The present problem however is the early detection ***** the virus as the currently available diagnostic tools are ei*****r time consuming (ELISA and Immunofluorescence) or highly sensitive without any conclusive detection. (PCR). A discussion of the epidemiology, transmission, and the latest research results and treatment methods would provide a better underst*****nding ***** the disease.

***** S*****RS Virus

Ever since ***** ***** of the epidemic in February ***** lab*****atories worldwide were *****volved in research to hasten ***** identification of the agent that was responsible for the symptoms of ***** pneumonia. The ***** health organization instituted a combined research by eleven laboratories on ***** 17th to speedup the research, as by then, the ***** was starting to take its toll. By ***** end ***** March *****ers in ***** Kong managed to find out traces of a novel coronavirus in the affected patients. By means ***** cell culture, electron microscopy and immuno-fluroscent antibody tests researchers ***** United States and Germany also confirmed the existence of a special type of coronavirus. Coronavirueses have the largest genome size ranging from 27 kb ***** 32 kb and ***** been well known to cause respiratory disorders in animals. Coronoviruses are easily transmitted by way of droplets, touch and small particulates in the air. They also have very ***** incubation periods as is ***** case with the SARS virus which has an incubation period between 2 and 7 days. On April *****th 2003 scientists working at the Michael Smith Genome Sciences center sucesfully mapped out ***** genetic sequence of the SARS virus making ***** for

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