Essay - Severe Acute Respiratory Syndrome Thesis Sars Epidemic Created a Medical...

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Severe Acute Respiratory Syndrome


***** epidemic created a medical emergency and a healthcare crisis with the loss of hundreds of lives in a short span of time. The knowledge of the etiology of ***** disease and the genome sequence ***** the virus provided new impetus in treatment of the *****. The crisis was successfully managed through an international cooperative effort ********** today we are better prepared to handle possible future outbreaks of the epidemic.


SARS is an acute infectious respiratory disease with all the symptoms of atypical pneumonia like fever, breathlessness that caused severe casualties in a short period ***** *****. ***** first *****stance of SARS infection was reported in November 2002 ***** the Guangdong province of china. The SARS epidemic ***** a panic worldover and ***** World Health Organization issued a global alert on March 12th 2003 about the rapid spread of symptoms of atypical pneumonia. Symptoms of ***** pneumonia *****re reported in Ch*****a and Hong Kong in February and March of ***** and SARS created ***** at the global level ***** 774 deaths and more than 8000 infected people. China, Taipei, Canada ***** Hong Kong suffered ***** most from the epidemic while sporadic ***** infections were found in many European nations and North America. Hundreds of people exhibiting symptoms were quarantined ***** treated for the complications until the SARS outbreak was fully contained. In July 2003 China officially announced the successful treatment of ***** last 12 cases of SARS. The present problem however is the early detection ***** the virus as the currently available diagnostic tools are either time consuming (ELISA and Immunofluorescence) or highly sensitive without any conclusive detection. (PCR). A d*****cussion of the epidemiology, transmission, ***** the latest research results and treatment methods would provide a ***** understanding of the disease.

The S*****RS Virus

Ever since the spread of the epidemic in ***** ***** laboratories worldwide were involved in research to hasten ***** identification of the agent ***** was responsible ***** the symptoms of atypical pneumonia. The ***** health organization instituted a combined research by eleven laboratories on ***** 17th to speedup the research, as by then, the virus was starting to take its toll. By ***** end of March researchers in ***** Kong ***** to f*****d out traces of a novel coronavirus in the affected patients. ***** means ***** cell culture, electron microscopy and immuno-fluroscent antibody tests researchers in United States and Germ***** also confirmed the existence of a speci*****l type of coronavirus. Coronavirueses have the largest genome size rang*****g from 27 kb to 32 ***** and ***** been well known to cause ***** disorders in animals. Coronoviruses are easily transmitted by way of droplets, touch ***** small particulates in the air. They also have very ***** incubation periods as is the case with the SARS virus which has an incubation period between 2 and 7 days. On April 12th 2003 scient*****ts working at the Michael Smith Genome Sciences center sucesfully mapped out ***** genetic ***** of the SARS virus making ***** for


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