Essay - Severe Acute Respiratory Syndrome Thesis Sars Epidemic Created a Medical...


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Severe Acute Respiratory Syndrome

Thesis

***** epidemic created a medical emergency and a healthcare crisis with the loss of hundreds of lives in a short sp*****n of time. The knowledge of the etiology of the disease ***** the genome sequence of the virus provided new impetus in treatment of the *****. The crisis was successfully managed through an international cooperative effort and today we are better prepared to h*****le possible future outbreaks of ***** epidemic.

*****

SARS is an acute infectious respiratory d*****ease ***** all the symptoms of atypical pneumonia like fever, breathlessness that caused severe casualties in a short period of *****. ***** first *****stance of SARS infection ***** reported in November 2002 in the Guangdong province of china. The ***** epidemic created a panic worldover and ***** World Health Organization issued a global alert on March 12th 2003 about the rapid spread of symptoms of atypical pneumonia. Symptoms of atypical pneumonia were reported in China and Hong Kong in February and ***** of 2003 and SARS created panic at ***** global level with 774 deaths and more than 8000 infected people. China, Taipei, Canada ***** Hong Kong suffered the most from the epidemic while sporadic ***** infections ***** found in many European nations and North America. Hundreds of people exhibit*****g symptoms were quarantined and treated for the complications until the SARS outbreak was fully contained. In July ***** China ********** announced ***** successful ***** of the last 12 cases of SARS. The present problem however is the early detection ***** the virus as the currently available diagnostic tools are ei*****r time consuming (ELISA ***** Immunofluorescence) or highly sensitive without any conclusive detection. (PCR). A d*****cussion of the epidemiology, transmission, and the latest research results and treatment methods would provide a ***** understanding of the disease.

***** S*****RS Virus

Ever since the ***** of the epidemic in ***** 2003 laboratories worldwide ***** *****volved in research to hasten ***** identification of the agent ***** was responsible for ***** symptoms of atypical pneumonia. The ***** health organization instituted a combined research by eleven laboratories on March 17th to speedup the *****, as by then, the virus was starting to take its *****ll. By ***** end ***** March researchers in H*****g Kong managed to find out traces of a novel coronavirus in the affected patients. ***** means ***** cell culture, electron microscopy and immuno-fluroscent antibody tests researchers ***** United States and Germany also confirmed the existence of a special type of coronavirus. Coronavirueses have the largest genome size ranging from 27 kb to 32 ***** and have been well known to cause respiratory disorders in animals. Coronoviruses are easily transmitted ***** way of droplets, touch and small particulates in the air. They also have very ***** incubation periods as is ***** case with the SARS virus which has an incubation period between 2 ***** 7 days. On April 12th 2003 scientists working at ***** Michael Smith Genome Sciences center suces***** mapped ***** the genetic sequence of the SARS virus making way for

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