Essay - Severe Acute Respiratory Syndrome Thesis Sars Epidemic Created a Medical...


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Severe Acute Respiratory Syndrome

Thesis

SARS epidemic created a medical emergency and a healthcare crisis with the loss of hundreds of lives in a short sp*****n of time. The knowledge of the etiology of ***** disease and the genome sequence ***** the virus provided new impetus in treatment of the *****. The crisis was successfully managed through an international cooperative effort ********** today we are better prepared to handle possible future outbreaks of the epidemic.

*****

SARS is an acute infectious respira*****ry disease ***** all ***** symptoms of atypical pneumonia like fever, breathlessness that caused severe casualties in a short period ***** *****. ***** first instance of SARS infection ***** reported in November 2002 in the Guangdong province of china. The SARS epidemic created a panic worldover and the World Health Organization issued a glob*****l alert on March 12th 2003 about the rapid spread of symptoms of atypical *****. Symptoms of atypical pneumonia *****re reported in China and Hong Kong in February and March of 2003 and SARS created ***** at ***** global level with 774 deaths and more than 8000 infected people. China, Taipei, Canada ***** Hong ***** suffered the most from the epidemic while sporadic SARS infections were found in many European nations and North America. Hundreds of people exhibiting ***** were quarantined ***** treated for ***** complications until the SARS outbreak was fully contained. In July 2003 China ********** announced the successful treatment of the last 12 cases of SARS. The present problem however is ***** early detection ***** the virus as the currently available diagnostic tools are ei*****r time consuming (ELISA and Immunofluorescence) or highly sensitive without any conclusive detection. (PCR). A discussion of the epidemiology, transmission, and the latest research results ***** treatment methods would provide a ***** understanding of the disease.

***** SARS Virus

Ever since ***** spread of the epidemic in ***** 2003 laboratories worldwide ***** involved in research to hasten ***** identification of the agent that was responsible for the symptoms of ***** pneumonia. The World health organization instituted a combined research by eleven laboratories on ***** 17th to speedup the *****, as by then, the virus was starting to take its *****ll. By the end ***** March researchers in Hong Kong managed to f*****d out traces of a novel coronavirus in the affected patients. ***** means of cell culture, electron microscopy and immuno-fluroscent antibody tests researchers in United States and Germ***** also confirmed the existence of a special type of coronavirus. Coronavirueses have the largest genome size ranging from 27 kb to 32 ***** and have been well known to cause respiratory disorders in animals. Coronoviruses are easily transmitted by way of droplets, touch and small particulates in the air. They also have very short incubation periods as is ***** case with the SARS virus which has an incubation period between 2 and 7 days. On April *****th 2003 scientists working at the Michael Smith Genome Sciences center suces***** mapped out ***** genetic ***** of the SARS virus making ***** for

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