Essay - Severe Acute Respiratory Syndrome Thesis Sars Epidemic Created a Medical...

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Severe Acute Respiratory Syndrome


***** epidemic created a medical emergency and a healthcare crisis with the loss of hundreds of lives in a short span of time. The knowledge of the etiology of the disease ***** the genome sequence ***** ***** virus provided new impetus in treatment of the disease. The crisis was successfully managed through an international cooperative effort and today we are better prepared to h*****le possible future outbreaks of ***** epidemic.


SARS is an acute infectious respira*****ry d*****ease ***** all the symptoms of atypical pneumonia like fever, breathlessness that caused severe casualties in a short period of *****. The first instance of SARS infection ***** reported in November 2002 in the Guangdong province of china. The SARS epidemic created a panic worldover and the World Health Organization issued a global alert on March 12th 2003 about the rapid spread of symptoms of atypical *****. Symptoms of ***** pneumonia *****re reported in China ***** Hong Kong in February and ***** of ***** and SARS ***** panic at the global level with 774 deaths and more than 8000 infected people. China, Taipei, Canada ***** Hong Kong suffered ***** most from the epidemic while sporadic ***** infections were found in many European nations and North America. Hundreds of people exhibiting ***** were quarantined and treated for ***** complications until the SARS outbreak was fully contained. In July 2003 ***** officially announced the successful ***** of ***** last 12 cases of SARS. The present problem however is the early detection ***** the virus as the currently available diagnostic tools are ei*****r time consuming (ELISA and Immunofluorescence) or highly sensitive without any conclusive detection. (PCR). A discussion of the epidemiology, transmission, and the latest research results ***** treatment methods would provide a better understanding ***** the disease.

***** S*****RS Virus

Ever since the ***** of the epidemic in February 2003 laboratories worldwide were *****volved in research to hasten the identification of the agent that was responsible for the symptoms of atypical pneumonia. The ***** health organization instituted a combined ***** by eleven l*****boratories on March 17th to speedup the research, as by then, the virus was starting to take its toll. By the end ***** March *****ers in H*****g Kong managed to find out traces of a novel coronavirus in the affected patients. ***** means of cell culture, electron microscopy and immuno-fluroscent antibody tests researchers in United States and Germ***** also confirmed the existence ***** a speci*****l type of coronavirus. Coronavirueses have the largest genome size rang*****g from 27 kb to 32 kb and ***** been well known to cause respiratory disorders in animals. Coronoviruses are easily transmitted ***** way of droplets, touch and small particulates in the air. They also have very short incubation periods as is ***** case with the SARS virus which has an incubation period between 2 ***** 7 days. On April 12th ***** scient*****ts working at ***** Michael Smith Genome Sciences center suces***** mapped out the genetic sequence of the SARS virus making way for


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