Essay - Severe Acute Respiratory Syndrome Thesis Sars Epidemic Created a Medical...


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Severe Acute Respiratory Syndrome

Thesis

SARS epidemic created a medical emergency and a healthcare crisis with the loss of hundreds of lives in a short sp*****n of time. The knowledge of the etiology of ***** disease ***** the genome sequence of the virus provided new impetus in treatment of ***** disease. The crisis was successfully managed through an international cooperative effort and today we are better prepared to handle possible future outbreaks of the epidemic.

Introduction

SARS is an acute infectious respiratory d*****ease ***** all ***** symptoms of atypical pneumonia like fever, breathlessness that caused severe casualties in a short period of time. The first *****stance ***** SARS infection ***** reported in November 2002 in the Guangdong province of china. The SARS epidemic created a panic worldover and the World Health Organization issued a global alert on March 12th 2003 about the rapid spread of symptoms of atypical *****. Symptoms of ***** pneumonia ********** reported in China ***** Hong Kong in February and ***** of ***** and ***** created panic at the global level with 774 deaths and more than 8000 infected people. China, Taipei, Canada ***** Hong Kong suffered ***** most from the epidemic while sporadic SARS infections were found in many European nations and North America. Hundreds of people exhibiting ***** were quarantined ***** treated for ***** complications until the ***** outbreak was fully contained. In July 2003 China ********** announced ***** successful ***** of the last 12 cases of SARS. The present problem however is ***** early detection ***** the virus as the currently available diagnostic tools are ei*****r time consuming (ELISA and Immunofluorescence) or highly sensitive without any conclusive detection. (PCR). A discussion of the epidemiology, transmission, and the latest research results ***** treatment methods would provide a better underst*****nding of the disease.

***** S*****RS Virus

Ever since the ***** of the epidemic in February ***** lab*****atories worldwide ***** ********** in research to hasten ***** identification of the agent ***** was responsible for ***** symptoms of atypical pneumonia. The World health organization instituted a combined rese*****rch by eleven laboratories on March 17th to speedup the research, as by then, the ***** was starting to take its toll. By the end of March *****ers in ***** K*****g ***** to f*****d out traces of a novel coronavirus in the affected patients. ***** means ***** cell culture, electron microscopy and immuno-fluroscent antibody tests researchers in United States and Germ***** also confirmed the existence of a speci*****l type of coronavirus. Coronavirueses have the largest genome size ranging from 27 kb to 32 ***** and ***** been well known to cause ***** disorders in animals. Coronoviruses are easily transmitted by way of droplets, touch and small particulates in the air. They also have very ***** incubation periods as is the case with the SARS virus which has an incubation period between 2 and 7 days. On April *****th 2003 scientists working at ***** Michael Smith Genome Sciences center suces***** mapped out the genetic sequence of the SARS virus making way for

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