Essay - Severe Acute Respiratory Syndrome Thesis Sars Epidemic Created a Medical...


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Severe Acute Respiratory Syndrome

Thesis

***** epidemic created a medical emergency and a healthcare crisis with the loss of hundreds of lives in a short span of time. The knowledge of the etiology of ***** disease and the genome sequence ***** the virus provided new impetus in treatment of the *****. The crisis was successfully managed through an international cooperative effort ********** today we are better prepared to handle possible future outbreaks of the epidemic.

*****

SARS is an acute infectious respiratory disease with all the symptoms of atypical pneumonia like fever, breathlessness that caused severe casualties in a short period ***** *****. ***** first *****stance of SARS infection was reported in November 2002 ***** the Guangdong province of china. The SARS epidemic ***** a panic worldover and ***** World Health Organization issued a global alert on March 12th 2003 about the rapid spread of symptoms of atypical pneumonia. Symptoms of ***** pneumonia *****re reported in Ch*****a and Hong Kong in February and March of ***** and SARS created ***** at the global level ***** 774 deaths and more than 8000 infected people. China, Taipei, Canada ***** Hong Kong suffered ***** most from the epidemic while sporadic ***** infections were found in many European nations and North America. Hundreds of people exhibiting symptoms were quarantined ***** treated for the complications until the SARS outbreak was fully contained. In July 2003 China officially announced the successful treatment of ***** last 12 cases of SARS. The present problem however is the early detection ***** the virus as the currently available diagnostic tools are either time consuming (ELISA and Immunofluorescence) or highly sensitive without any conclusive detection. (PCR). A d*****cussion of the epidemiology, transmission, ***** the latest research results and treatment methods would provide a ***** understanding of the disease.

The S*****RS Virus

Ever since the spread of the epidemic in ***** ***** laboratories worldwide were involved in research to hasten ***** identification of the agent ***** was responsible ***** the symptoms of atypical pneumonia. The ***** health organization instituted a combined research by eleven laboratories on ***** 17th to speedup the research, as by then, the virus was starting to take its toll. By ***** end of March researchers in ***** Kong ***** to f*****d out traces of a novel coronavirus in the affected patients. ***** means ***** cell culture, electron microscopy and immuno-fluroscent antibody tests researchers in United States and Germ***** also confirmed the existence of a speci*****l type of coronavirus. Coronavirueses have the largest genome size rang*****g from 27 kb to 32 ***** and ***** been well known to cause ***** disorders in animals. Coronoviruses are easily transmitted by way of droplets, touch ***** small particulates in the air. They also have very ***** incubation periods as is the case with the SARS virus which has an incubation period between 2 and 7 days. On April 12th 2003 scient*****ts working at the Michael Smith Genome Sciences center sucesfully mapped out ***** genetic ***** of the SARS virus making ***** for

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