Essay - Severe Acute Respiratory Syndrome Thesis Sars Epidemic Created a Medical...


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Severe Acute Respiratory Syndrome

Thesis

***** epidemic created a medical emergency and a healthcare crisis with the loss of hundreds of lives in a short sp*****n of time. The knowledge of the etiology of the disease ***** the genome sequence of ***** virus provided new impetus in treatment of the *****. The crisis was successfully managed through an international cooperative effort and today we are better prepared to h*****le possible future outbreaks of ***** epidemic.

Introduction

SARS is an acute infectious respiratory disease ***** all the symptoms of atypical pneumonia like fever, breathlessness that caused severe casualties in a short period of time. ***** first instance of SARS infection was reported in November 2002 ***** ***** Guangdong province of china. The ***** epidemic created a panic worldover and the World Health Organization issued a global alert on March 12th 2003 about the rapid spread of symptoms of atypical pneumonia. Symptoms of ***** pneumonia were reported in China ***** Hong Kong in February and March of 2003 and SARS ***** panic at ***** global level with 774 deaths and more than 8000 infected people. China, Taipei, Canada and Hong ***** suffered the most from the epidemic while sporadic ***** infections ***** found in many European nations and North America. Hundreds of people exhibit*****g ***** were quarantined and treated for ***** complications until the SARS outbreak was fully contained. In July 2003 China officially announced ***** successful treatment of the last 12 cases of SARS. The present problem however is ***** early detection ***** the virus as the currently available diagnostic tools are either time consuming (ELISA and Immunofluorescence) or highly sensitive without any conclusive detection. (PCR). A d*****cussion of the epidemiology, transmission, ***** the latest research results and treatment methods would provide a ***** understanding of the disease.

***** S*****RS Virus

Ever since ***** spread of the epidemic in February ***** laboratories worldwide were involved in research to hasten the identification of the agent ***** was responsible for the symptoms of atypical pneumonia. The World health organization instituted a combined ***** by eleven l*****boratories on ***** 17th to speedup the research, as by then, the ***** was starting to take its *****ll. By the end of March researchers in H*****g Kong ***** to f*****d out traces of a novel coronavirus in the affected patients. By means of cell culture, electron microscopy and immuno-fluroscent antibody tests researchers in United States and Germ***** also confirmed the existence ***** a special type of coronavirus. Coronavirueses have the largest genome size ranging from 27 kb ***** 32 ***** and have been well known to cause respiratory disorders in animals. Coronoviruses are easily transmitted by way of droplets, touch and small particulates in the air. They also have very ***** incubation periods as is the case with the SARS virus which has an incubation period between 2 ***** 7 days. On April *****th 2003 scient*****ts working at the Michael Smith Genome Sciences center sucesfully mapped out ***** genetic ***** of the SARS ***** making way for

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