Essay - Severe Acute Respiratory Syndrome Thesis Sars Epidemic Created a Medical...


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Severe Acute Respiratory Syndrome

Thesis

SARS epidemic created a medical emergency and a healthcare crisis with the loss of hundreds of lives in a short span of time. The knowledge of the etiology of ***** disease and the genome sequence ***** the virus provided new impetus in treatment of the *****. The crisis was successfully managed through an international cooperative effort ********** today we are better prepared to handle possible future outbreaks of ***** epidemic.

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SARS is an acute infectious respira*****ry d*****ease with all the symptoms of atypical pneumonia like fever, breathlessness that caused severe casualties in a short period of time. ***** first instance ***** SARS infection was reported in November 2002 ***** ***** Guangdong province of china. The SARS epidemic ***** a panic worldover and the World Health Organization issued a glob*****l alert on March 12th 2003 about the rapid spread of symptoms of atypical pneumonia. Symptoms of atypical pneumonia *****re reported in China ***** Hong Kong in February and ***** of 2003 and ***** created panic at the global level ***** 774 deaths and more than 8000 infected people. China, Taipei, Canada and Hong ***** suffered the most from the epidemic while sporadic SARS infections were found in many European nations and North America. Hundreds of people exhibit*****g ***** ***** quarantined ***** treated for the complications until the SARS outbreak ***** fully contained. In July ***** China officially announced the successful ***** of ***** last 12 cases of SARS. The present problem however is the early detection of the virus as the currently available diagnostic tools are either time consuming (ELISA and Immunofluorescence) or highly sensitive without any conclusive detection. (PCR). A discussion of the epidemiology, transmission, ***** the latest research results and treatment methods would provide a better underst*****nding of the disease.

***** S*****RS Virus

Ever since ***** ***** of the epidemic in ***** 2003 laboratories worldwide were involved in research to hasten the identification of the agent that was responsible ***** the symptoms of atypical pneumonia. The World health organization instituted a combined research by eleven laboratories on March 17th to speedup ***** *****, as by then, the ***** was starting to take its toll. By the end of March researchers in ***** Kong ***** to f*****d out traces of a novel coronavirus in the affected patients. ***** means of cell culture, electron microscopy and immuno-fluroscent antibody tests researchers in United States and Germany also confirmed the existence ***** a speci*****l type of coronavirus. Coronavirueses have the largest genome size rang*****g from 27 kb to 32 kb and have been well known to cause respiratory disorders in animals. Coronoviruses are easily transmitted ***** way of droplets, touch and small particulates in the air. They also have very short incubation periods as is the case with the SARS virus which has an incubation period between 2 and 7 days. On April 12th ***** scientists working at the Michael Smith Genome Sciences center suces***** mapped out the genetic sequence of the SARS ***** making ***** for

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