Application Disorders of the Veins and Arteries Research Paper

Pages: 2 (794 words)  ·  Bibliography Sources: 2  ·  File: .docx  ·  Level: Master's  ·  Topic: Anatomy

Disorders of the Veins and Arteries

Chronic venous insufficiency and the deep venous thrombosis fall within the most common medical issues that the adult population is vulnerable to. These disorders have very common symptoms but mostly those symptoms are mistakenly diagnosed for a different medical problem. Earlier these disorders were thought to be of a simple nature but recent researches have shown that the cellular and molecular aspects of these disorders show 'complex multifactorial processes are reflecting both systemic abnormalities of connective tissue synthesis and cellular inflammatory reaction.' (Chieh-Min Fan, 2005).

Pathaphysiology of CVI and DVT

It is believed that the chronic venous insufficiency (CVI) in the veins occurs primarily because of the weakness of the vein walls. A regular normal vein includes compliance providing elastic fibers, strength providing collagen matrix, and three layers of smooth muscle that aid in controlling the tone of the vein. In most cases it is understood that the muscle layers' distortion and disruption leads to the proliferation of the collagen matrix. The more the infected area, the more are the disrupted muscle layers, leaving the collagen matrix and the elastic layers vulnerable. As a result of this alteration, the veins lose contractility and result in vessel dilation whilst responding to the hypertension in the veins.

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Deep vein thrombosis (DVT) is the clotting of blood in the veins. The parts mostly affected are the thigh and the calf veins in the popliteal vein, iliofemoral vein, and the femoral vein. However, DVT can also occur in arms. The occurrence of DVT in the veins is primarily due to a tissue factor. This factor resultantly converts prothrombin into thrombin, which consequently is followed by the deposition of fibrin. The fibrin and the red blood cells combined, deposit themselves on the endothelium, a wall lining of the blood vessels whose purpose itself is to stop blood clotting (Lopez JA, 2009). This deposition mostly initiates in the valves of the vein. The blood pattern flow in the veins cause the oxygen concentration levels in the blood to fall. Thus, the blood clot begins to grow inside the veins, causing DVT.

TOPIC: Research Paper on Application Disorders of the Veins and Arteries Assignment

Difference between venous and arterial thrombosis

A thrombosis can be understood as a blood clot that occurs in the blood vessels. As identified, venous thrombosis occurs in the veins and is mostly commonly found in the calf and the thigh veins. Arterial thrombosis, however, is the… [END OF PREVIEW] . . . READ MORE

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