Research Proposal: Bacteria Effect of Date Extract

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[. . .] The microbiologists have come across the fact that the aqueous extract of the dry dates has the quantity dependent property to inhibit the superoxide and the hydroxyl radicals. It is acknowledged that in the method of riboflavin photo reduction the amount of fresh extract that is used to scavenge the superoxide radical (50%) is equivalent to the 0.7 to 0.8 mg/ml of dry date extract. Similarly in the deoxyribose degradation method the dry date extract required to scavenging 50% hydroxyl radical amounted to 2.0 to 2.2 mg/ml. It is therefore observed that 1.5 to 2.0 mg/ml and 4.0 to 4.2mg/ml concentrations of the date extract has the potency to respectively inhibit superoxide and hydroxyl radicals (Dandamayev 2002).

The anti-inflammatory activity of date extract

The methanol component with the diluted extract of the fleshy date indicated that the extract has a tendency to help overcoming the blurs and foot swelling by the portion of 61.3% to the level of 68.7%. It was also obtained from the examination of the extract that the extract of the fleshy as well as dry dates can reduce the adjuvant arthritis by approximately 35.5%. This is accomplished chiefly by the activity that calls for mechanistically reducing ESR and plasma fibrinogen and normalizing the plasma level of antioxidants. The careful administration, preparation, and examination of the date extract also indicated that the extract has the healing tendency, antioxidant potency followed by the natural methods that can help increase the body weight and gaining the higher food efficiency ratios (Varisco 2006).

In vitro effects of the date extracts

The measure in g/mlcrude acetone extracts of date palm pit on quantity basis of 100 and 1000 indicated an in fluxing, powerful and quantity / dose dependent capacity of the date extract to naturally inhibit the infectiveness and disease causing aspect of the of Pseudomonas phage ATCC 14209-B1 to Pseudomonas aeruginosa, this action of the date extract is executed by means of binding to the phage, with the required minimum inhibiting concentration (MIC) of approximately about
The obtained results shed light on the aspect of the date extract, that the pit extract Phoenix dactylifera (date) fruit has a natural potency that could serve to take an important role in a controlling the replication of HIV-1 (Human Immuno Deficiancy virus) by means of a new yet natural process of interaction with binding of the phage to the host bacterium and injection of its genome that shows its use in the treatment of AIDS (Aquired Immuno deficiancy Syndrome) that has already been known an incurable epidemics throughout the world (Mcalpin 2003).

Presently the treatment for HIV infection comprises of highly active antiretroviral therapy that comes with the guaranteed side effects of lipodystrophy, dyslipidaemia, diarrhea, insulin resistance, an increase in cardiovascular risks and birth deprivations, it is therefore worth acknowledging that the Phoenix dactylifera (date) can prove to be a new medication for the treatment of AIDS and resulting into minimum rather no side effects.

Effect of date extracts on the streptococcus pyogenes

Phoenix dactylifera (date) fruit extract at various levels of 5%, 10% and 20% dilution when incubated with Streptococcus pyogenes for 24 hours gave a clear picture that they have an ability to retard the growth of the Streptococcus pyogenes upto 30.8%, 64.7% and 88.5%, respectively. This was duly advocated because the date extract was found to have neutralizing impact of the hemolytic activities the streptococcal exotoxin, streptolysin O. And is equally potent inhibition up to 96% was observed at a dilution of extract as low as 1:262144 Date Extract dilution.

Summary

The microbiologists have come across the fact that the aqueous extract of the dry dates has the quantity dependent property to inhibit the superoxide and the hydroxyl radicals. It is acknowledged that in the method of riboflavin photo reduction the amount of fresh extract that is used to scavenge the superoxide radical (50%) is equivalent to the 0.7 to 0.8 mg/ml of dry date extract. Similarly in the deoxyribose degradation method the dry date extract required to scavenging 50% hydroxyl radical amounted to 2.0 to 2.2 mg/ml. It is therefore observed that 1.5 to 2.0 mg/ml and 4.0 to 4.2mg/ml concentrations of the date extract has the potency to respectively inhibit superoxide and hydroxyl radicals.

The dates are domestically consumed and found cultivated in the Arabian countries. Owing to the favorability of climate the growth of date palm is observed on a large scale in these countries. Apart from the Arabian countries dates are widely consumed throughout the world. The medical professionals and the microbiologist have decoded the two major benefits of the date extract, which is the antioxidant and anti-mutagenic properties of date extract in vitro. The microbiologists have come across the fact that the aqueous extract of the dry dates has the quantity dependent property to inhibit the superoxide and the hydroxyl radicals.

It is acknowledged that in the method of riboflavin photo reduction the amount of fresh extract that is used to scavenge the superoxide radical (50%) is equivalent to the 0.7 to 0.8 mg/ml of dry date extract. Similarly in the deoxyribose degradation method the dry date extract required to scavenging 50% hydroxyl radical amounted to 2.0 to 2.2 mg/ml. It is therefore observed that 1.5 to 2.0 mg/ml and 4.0 to 4.2mg/ml concentrations of the date extract has the potency to respectively inhibit superoxide and hydroxyl radicals. Similarly it is also identified as the property of the water-based date extract that it has a potency to inhibit the lipid per oxidation as well as the protein oxidation in the quality dependent aqueous forms.

The date extract upon decoding also revealed the presence of the four types of free phenolic acids that are protocatechuic acid, vanillic acid, syringic acid, and ferulic acid. The nine bounded phenolic acids were also found to be available including gallic acid, protocatechuic acid, p-hydroxybenzoic acid, vanillic acid, caffeic acid, syringic acid, p-coumaric acid, ferulic acid, and o-coumaric acid. The TLC (Thin Layer Chromatography) also revealed the astonishing aspect of the date extract; it mentioned the presence of some useful natural steroids including cholesterol, stigmasterol, campesterol and ?-sitosterol. Anthocyanins. The similar thin layer chromatography presented the findings that the date extract also contains an ample amount of carotenoid pigments in the form of lutein and carotene. The gas liquid analysis and chromatography of the date extract further revealed that the of oleic, lauric, palmitic, Capric, myristic, myristoleic, palmitoleic, stearic, linoleic and linolenic acids are also present in the date extract.

The date extracts also showed the tendency of quantity based inhibition of benzo (a)pyrene-induced muta-genecity on Salmonella tester strains TA-98 and TA-100 with metabolic activation. It has also been observed to the property of date extract to inhibit the His+ revertant formation in TA-98 and TA-100, respectively by 50% simply by 3.6mg/plate and 4.3mg/plate. These properties of the date extract conclude that the antioxidant and the anti-mutagenic activities of the date extract have high functional potency as a medication as well as food item. And this is implied by the presence of compounds with potent free-radical-scavenging activity. Hence this can be mounted that the date extract has a high tendency to be used a medication, the TLC (Thin Layer Chromatography) also revealed the astonishing aspect of the date extract; it mentioned the presence of some useful natural steroids including cholesterol, stigmasterol, campesterol and ?-sitosterol. Anthocyanins. The similar thin layer chromatography presented the findings that the date extract also contains an ample amount of carotenoid pigments in the form of lutein and carotene.

During the time span of inhibiting the lipid per oxide the 2.0 mg/ml date extract was observed to inhibit the TBARS completely, that were found in the early stages of the incubation and the tendency of inhibition gradually increased in the later stages of the incubation period of lipid per oxide study. In the similar manner in the high Fe2+/ascorbate induction system a 2.3 mg/ml concentration of the date extract inhibited carbonyl formation that was measured by DNPH reaction at 50% concentration. The study of the concentration of date extract by 4.0 to 4.5 mg/ml indicated that the lipid per oxide and protein carbonyl formation was completely inhibited.

References

Bostoen, Koen. 2005. "A Diachronic Onomasiological Approach to Early Bantu Oil Palm Vocabulary." Studies in African Linguistics 34:113+. Retrieved September 25, 2011 (http://www.questia.com/PM.qst?a=o&d=5034944701).

Bringeus, Nils-Arvid. 2003. "The Rest on the Flight into Egypt: A Motif in Scandanavian Folk Art." Folklore 114:323+. Retrieved September 25, 2011 (http://www.questia.com/PM.qst?a=o&d=5006399281).

Dandamayev, M.A. 2002. "Das Egibi-Archiv, I: Die Felder Und Garten, 2 Vols." The Journal of the American Oriental Society 122:105+. Retrieved September 25, 2011 (http://www.questia.com/PM.qst?a=o&d=5000841255).

Kapp, Dieter B. 1994. "A Collection of Jaffna… [END OF PREVIEW]

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Bacteria Effect of Date Extract.  (2011, September 26).  Retrieved June 19, 2019, from https://www.essaytown.com/subjects/paper/bacteria-effect-date-extract/2060873

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"Bacteria Effect of Date Extract."  26 September 2011.  Web.  19 June 2019. <https://www.essaytown.com/subjects/paper/bacteria-effect-date-extract/2060873>.

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"Bacteria Effect of Date Extract."  Essaytown.com.  September 26, 2011.  Accessed June 19, 2019.
https://www.essaytown.com/subjects/paper/bacteria-effect-date-extract/2060873.