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Alzheimer's Disease Examining Multiple Chapters

… Variants of APP from mice were re-injected after allelic regeneration and exposed to the beta secretase enzyme. The genes generated targeted separate lines of knock-in mice on the APP cut differently (Ring et al., 2007).

The authors sought to identify the primary sites of APP where the beta secretase would target possibly when truncated. With the use of the mice, it is evident that the physiology of the APP is critical in determining the nature of dementia to be experienced. The in vivo introduction of stop codons in two loci obtained from the APP's chromosome elucidated invaluable results. The mutants of the knocked in mice attenuated the same defects as seen in wild type mice (Luo et al., 2001). However, the mice that lacked the…. [read more]


Alzheimer's Disease: The Onset as Alzheimer's Diseases Term Paper

… Alzheimer's Disease: The Onset

As Alzheimer's diseases is believed to be the "dementing order" because of the recognized changes in the behavior and line of thinking of the person with the said disease. From the researchers' and the physicians' point-of-view, there is a possibility that anyone can get it, regardless of the age. More so, people should realize that Alzheimer's disease is not really a normal part of aging. It is not something that is inevitable. There are some people who reached the age of 75 and up who are not even suffering from any dementing disorder. Because of this, it should be considered that Alzheimer's disease is actually "an exception, rather than the rule, of old age" (Light and Lebowitz, 1989).

There are enough…. [read more]


Alzheimer's Disease Has Become a Concern Thesis

… Alzheimer's Disease has become a concern that is now more widely studied than it used to be. Typically seen in the elderly population, Alzheimer's disease is characterized by several factors, including forgetfulness and agitation (National, 2008). Currently, there is no cure for Alzheimer's disease, and it gets progressively worse as the patient continues to age (National, 2008). Despite the lack of a cure, however, there are some treatments that are just coming to light where Alzheimer's disease is concerned (Mace & Rabins, 2006). In other words, doctors and researchers are working on ways to be able to slow the progression of the disease and to ease the symptoms of the disease, and there are some medications that do show some promise at this point (Medina,…. [read more]


Alzheimer's Disease and Aging at What Age Term Paper

… Alzheimer's Disease And Aging

At what age do people start to get Alzheimer's?

Alzheimer disease (AD) usually does not start until around 65 years of age or older. It is characterized by gradually worsening dementia (forgetfulness) caused by cerebral atrophy (deterioration). It is the most common form of dementia. Fewer than 2% of families with AD have early-onset familial AD (EOFAD), in which symptoms occur before the age of 65 years. EOFAD only refers to families in which multiple cases of AD occur. Early onset may happen in the 40s or early 50s, although early onset in the 30s has been reported. Sixty-one percent of individuals with early-onset AD had a positive family history and thirteen percent affected individuals in three generations. EOFAD is not…. [read more]


Alzheimer's Disease Howenstine, J.A. ) Research Paper

… Alzheimer's Disease

Howenstine, J.A. (2010) How to heal Alzheimer's disease. Townsend Letter 321: 78-85

This is a peer-reviewed 15-page article by James a. Howenstine, MD, a board-certified specialist in internal medicine, who is convinced that natural therapies are more effective, safer, and less expensive than pharmaceutical drugs for Alzheimer's disease treatment. The report includes a list of the items that can destroy the myelin sheath surrounding neurons, and thus greatly increase the risk of being a victim of Alzheimer's disease in one's lifetime. These items can have an effect on a person's neurology from childhood on. Howenstine argues that Alzheimer's is a disease of advanced civilization, and there are technological advancements in modern-day society that have furthered its prevalence. One of these technologies is electric…. [read more]


Alzheimer's Disease Is a Neuro-Degenerative Disorder Term Paper

… Alzheimer's disease is a neuro-degenerative disorder that currently affects close to 4 million people in the United States (National Institutes of Health). By 2025, the number of Alzheimer's cases is expected to increase by 44% in the United States (Alzheimer's Association, Fact Sheet). From the onset of symptoms, Alzheimer's disease can last from 30 to 20 years (Alzheimer's Association, Alzheimer's).

There are two main types of Alzheimer's disease: familial Alzheimer's, and sporadic Alzheimer's. Genes are directly linked in cases of familial Alzheimer's disease. Most cases of familial Alzheimer's occur before the age of 60, while cases of sporadic Alzheimer's mostly occur after the age of 60. Sporadic Alzheimer's disease is not linked to genes. In familial Alzheimer's disease, individuals have a mutation or abnormal variation…. [read more]


Alzheimer Healthy Community Planned Literature Review

… Nonetheless, available evidence underscores its significant influence over the psychological well-being of older people in the community or institutions as a companion (Williams & Jennings).

Attendance in Adult Day Care Centers of Cognitively Intact Older Persons

This research conducted interviews and a structured questionnaire in exploring the reasons for the non-use of adult day care centers or ADCCs and the reason for their use by those at those centers (Iecovich & Biderman, 2013). Sample populations were 819, 417 of whom are users of ADCCs and 402 are non-users in the southern region of Israel.

Results showed that the most common reasons for not using ADCCs were accessibility barriers, characteristics of the participants and of the ADCCs, lack of need for the service, and personal difficulties.…. [read more]


Alzheimer's Adult Daycare for Patients Literature Review

… Vreugdenhil, Anthea, Cannell, John, Davies, Andrew, and Razay, George. (2011). A community-based exercise programme to improve functional ability in people with Alzheimer's disease: A randomized controlled trial. Scandinavian Journal of Caring Sciences, 26(1), 12-19.

When evaluating an ideal daycare setting to benefit an individual suffering from an advancing Alzheimer's or dementia-related condition, it is important to consider so of the most highly recommended interventions for such subjects. An important benefit of adult daycare utilization is the higher degree of direct physical engagement that it affords the patient. This concept is articulated in the research by Vreugdenhil et al. (2011), which considers the importance of maintaining a steady exercise regimen for a given patient. According to the article, "at 4-months follow-up, patients who exercised, compared with…. [read more]


Alzheimer's Disease Currently Affects Term Paper

… One area of cognitive-behavioral research into the prevention of Alzheimer's involves the study of the link between leisure pursuits and dementia prevention. Specifically, investigators believe that activities such as chess, crosswords or reading that engage a person's cognitive abilities may have some ability to prevent the development of Alzheimer's. A study done in 2003 (Vergese et al.) examined the effects of various activities on cognitive functioning and their ability to prevent development of Alzheimer's. The leisure activities were broken down into two main categories; cognitively based ones, and physical activities. The cognitive activities examined were; reading, writing for pleasure, crossword puzzles, board games/cards, group discussions and playing instruments. The physical activities were; tennis/golf, swimming, cycling, dancing, group exercises, team games, walking, stair climbing, housework and…. [read more]


Alzheimer's Disease Is the Seventh Leading Cause Research Paper

… Alzheimer's disease is the seventh leading cause of all deaths in the United States and the fifth leading cause of death in Americans who are 65 years of age or older. The reason that the number of people afflicted with Alzheimer's is growing so fast is simple: the baby boom generation is quickly becoming the older generation. This paper presents factual data about this dreaded disease, and unfortunately it reflects that fact that the literature available in scholarly and in popular publications does not seem optimistic about a formula for prevention or for a cure. As of 2008, about 5.2 million Americans had Alzheimer's; of those, 5 million were 65 years of age or older. In fact one in eight persons 65 or over --…. [read more]


Alzheimer's Treatment Term Paper

… Alzheimer's Treatment

Alzheimer disease is a ubiquitous form of dementia which is common among the elderly people. The person's abilities in undertaking his normal daily activities are affected by this disorder of the brain. This condition starts slowly where the parts of the brain controlling the memory thought and language are involved. It manifests itself from the initial forgetfulness of minor duties to the actual display of aggression and depression. There is no cure currently for this Alzheimer but the behavioral and cognitive symptoms can be treated by various drugs and other non-drugs forms. This paper will consider the different treatment for Alzheimer. Different medications and nutrition and other remedy like neurotransmitters will be analyzed. Various case studies of the treatments will be evaluated also.…. [read more]


Alzheimer's Disease Essay

… This is the point that they can be able to introduce effective treatment options in helping to find a cure. ("African-Americans and Alzheimer's," 2011)

What role do social and/or cultural influences play in the disease for a particular population? What are the effects of the populations' beliefs and values have on treatment options?

Social and cultural factors are impacting the total amount of African-Americans that are being affected by the condition. Where, there is a preconceived notion to ignore the most common warning signs and the effects that it is having on this segment of the population. This makes the onset of dementia more likely to occur, which will lead to the early stages of Alzheimer's disease beginning. ("African-Americans and Alzheimer's," 2011)

The way that…. [read more]


Alzheimer's Immunology Essay

… Alzheimer's Immunology

Alzheimer's disease (AD) has become widely associated with aging since its "re-discovery" and accompanying research in the 1970s. In fact, AD is thought to affect over 25 million people worldwide (Lemere & Masliah, 2010). AD is diagnosed as a result of "progressive memory loss and a decline in cognitive abilities" (Lemere & Masliah, 2010). Many pathological conditions are thought to contribute to the onset and progression of AD, including: amyloid-? (a?) peptide extracellular plaques, tau protein aggregates from intracellular neurofibrillary tangles, gliosis, inflammation, neuritic dystrophy, neurotransmitter level changes, and overall neuron loss (Lemere & Masliah, 2010). Currently, there are no "disease-modifying therapies" available for the treatment of AD (Lemere & Masliah, 2010).

Research on AD and possible therapies has been abundant for decades.…. [read more]


Alzheimer's Disease According to the American Term Paper

… ALZHEIMER'S DISEASE

According to the American Alzheimer's Association, Alzheimer's is a progressive and fatal brain disease which currently affects more than five million Americans and as a disease "destroys brain cells, causing problems with memory, thinking and behavior" and can negatively affect a person's overall lifestyle and social life. Alzheimer's is also the most common form of dementia, known in the past as senile dementia or common senility, and currently, no cure is known, yet researchers have managed to come up with treatments for the symptoms of Alzheimer's which can extend a person's life by many years if treatment is done early ("What Is Alzheimer's?" 2008, Internet).

DESCRIPTION of the DISEASE:

As to the disease of Alzheimer's as it relates to physiology and biology, the…. [read more]


Alzheimer's Disease Essay

… Treatment

No cure exists for Alzheimer's disease. However, research indicates that certain lifestyle factors can have a formidable impact in preventing the illness. Individuals who engage in regular physical activity are 50% less likely to develop the disease, a rate which increases to 60% for women who exercise (Peeke 2004: 8). Regular use of non-steroidal anti-inflammatory drugs (NSAIDs) like aspirin or ibuprofen has also been correlated with lower rates of the illness: a 35% reduction in the in one study. Maintaining a healthy weight; engaging in sustained mental activity; and eating many fruits and vegetables high in antioxidants, fish high in omega-3 fatty acids, and nuts have all been linked to lower rates of Alzheimer's. Diet and exercise, along with a low-dose aspirin regime, may…. [read more]


Alzheimer's Disease Stages Term Paper

… As the disease spreads and worsens, the tasks will have to change accordingly and the skills and abilities will have to be rechecked in order to fix the tasks to adjust the routine. It is important for the families and communities to work together to create a successful environment to keep the mind of the patient stable.

The four essential categories of activities that take up our time in the course of a day are work, self-care, leisure and resting. It is important to however maintain a balance between these and manage the stress levels and keep our day positive and then has a control over our lives. The negative impacts are quite clear if this balance is not maintained. A day full of work…. [read more]


Alzheimer's Disease Is a Fatal Neurological Condition Term Paper

… Alzheimer's disease is a fatal neurological condition that typically appears first in elderly individuals; it is a progressive disease with no cure that causes the gradual deterioration of cognitive functions, eventually rendering patients completely incoherent and unable to process cognitive information or to communicate (Taylor, Lillis, & LeMone, 2008). The only definitive way to formally diagnose Alzheimer's disease is through a post-mortem identification of tangled neuron bundles and amyloid plaque at autopsy. However, the symptoms of the disorder are distinctive enough that they permit a practical diagnosis for the purpose of treatment (Taylor, Lillis, & LeMone, 2008).

While there is no way to stop the progression of the disease yet, early diagnosis is a benefit because it permits caretakers and patients to mitigate some of…. [read more]


Alzheimer's Disease Is a Progressive Research Proposal

… Alzheimer's disease is a progressive, neurodegenerative disease characterized by memory loss, language deterioration, impaired ability to mentally manipulate visual information, poor judgment, confusion, restlessness, and mood swings. Alzheimer's disease is a form of a mental disorder known as dementia. Dementia is a brain disorder that causes the loss of mental functions; such as thinking, memory, and reasoning. Dementia is not a disease itself, but rather a group of symptoms that are caused by various diseases or conditions. It restricts the brain's ability to process rational or normal thought and prevents normal daily activities.

Alzheimer's disease usually begins after age 65, but its onset may occur as early as age 40, appearing first as memory decline and, over several years, destroying cognition, personality, and ability to…. [read more]


Alzheimer's Early Onset Alzheimer's Disease Medically Speaking Essay

… ALZHEIMER'S

EARLY ONSET ALZHEIMER'S DISEASE

Medically speaking, Alzheimer's disease, named after German neurologist Alois Alzheimer in 1864, is also known as senile dementia and is characterized by mental confusion, memory loss, disorientation, restlessness, speech disturbances, the inability to walk or sit properly and sometimes hallucinations. The person afflicted with this disease may often refuse to eat and may be unable to feed oneself and lose control of bowel movements. Under most circumstances, Alzheimer's disease begins in the later years of life after the age of 65 with slight defects in memory and behavior and occurs with equal frequency in men and women. In the human brain, Alzheimer's is based upon certain types of plaque that accumulate in the cerebral cortex and on the surfaces of…. [read more]


Alzheimer's Disease (Ad) Term Paper

… 1 (1995): 113-129.

A www.questia.com/PM.qst?action=openPageViewer&docId=77518217

Grober, Ellen, and Shereen Bang. "Sentence Comprehension in Alzheimer's Disease." Developmental Neuropsychology 11.1 (1995): 95-107.

A www.questia.com/PM.qst?action=openPageViewer&docId=5001953321

Ingram, Vernon. "Alzheimer's disease: the molecular origins of the disease are coming to light, suggesting several novel therapies." American Scientist July-Aug. 2003: 312+. http://www.questia.com/.

Luchsinger JA, Tang MX, Shea S, Mayeux R. Aug 2002. Caloric intake and the risk of Alzheimer disease. Arch Neurol. Taub Institute for Research of Alzheimer's Disease and the Aging Brain, Columbia University;59(8):1258-63.

Poirier et al. 1995 Apolipoprotein E4 allele as a Predictor of cholinergic defects and treatment outcome in Alzheimers Diseacease. National Academy of Sciences. Vol. 92, 12260-12264.

A www.questia.com/PM.qst?action=openPageViewer&docId=85911675

Powell, Lenore S., and Katie Courtice. Alzheimer's Disease A Guide for Families. Reading, MA: Perseus Publishing, 1993.

Robinson,…. [read more]


Treatment of Women Diagnosed With Dysthymia Term Paper

… Treatment of Women Diagnosed With Dysthymia

This proposal for a clinical case study of the treatment of a woman diagnosed with dysthymia employs a cognitive behavioral approach to identifying effective treatment modalities for patients with depressive disorders. In cognitive behavioral sessions, psychotherapists seek to help a patient identify his or her harmful thinking patterns in order to develop better coping strategies and social skills. The focus of the research in this study is on how people in general think, behave, and communicate in the present rather than on their early childhood experiences.

Proposal for a Clinical Case Study Dissertation - Doctor of Psychology in Clinical Psychology

Chapter One. Introduction

Statement of the Problem

Hypothesis

Rationale

Chapter Two: Review of the Relevant Literature

Background and Overview…. [read more]


Alzheimer's Disease Term Paper

… ¶ … Alzheimer's disease. Specifically, it will briefly describe the disease, and then focus on its causes, symptoms, and the population likely to suffer from the disease, and its prevention and treatments. Alzheimer's disease is a devastating condition that affects millions of Americans every year. It has recently received more attention because of the suffering of prominent people, such as the late President Ronald Reagan, and actor Charlton Heston. New research into Alzheimer's disease may find a cure, or at least medication that can slow down the onset of this devastating and as yet incurable disease.

Alzheimer's disease affects the brain and causes dementia, usually in aging patients. It is usually a gradual procession, that systematically "destroys a person's memory and ability to learn, reason,…. [read more]


Dementia Alzheimer's Disease Term Paper

… They are believed to produce a neurotoxic effect and are akin to functionless brain scar tissue.

3. Neurofibrillary Tangles. The neurofilaments of a neuron are the skeletal structures of the cell and serve as the transport system for components within the neuron. When these become malformed the cells cannot function properly nor send messages to other neurons. Tangles also lead to cell death.

Third, there is no cure for AD. AD is progressive and is 100% fatal (although many elderly patients may die from other complications). There are many conditions that mimic dementia and are reversible. The average expected lifespan for a person diagnosed with early AD is about seven to eight years, but the course can last anywhere from one to twenty years (Molsa,…. [read more]


Alzheimer's Disease Is a Highly Prevalent Condition Article Critique

… ¶ … Alzheimer's disease is a highly prevalent condition among older people. This makes it important for physicians to deliver the news in such a way that the person in question and the family can make suitable and effective arrangements for coming to terms with the diagnosis.

The article raises several important and surprising points. The first of these is that physicians tend to be reluctant to give the diagnosis, especially at the beginning stages of dementia, when there is not yet any certainty about the nature or prognosis of the specific condition. The result of this is that treatment regimes and coping mechanisms can only be implemented later, when the illness has progressed to the extent where intervention strategies would be far less effective…. [read more]


Alzheimer's Disease Has Developed Term Paper

… Using PET it is possible to even identify the minute details such as the number of receptors within particular areas of the brain. This in turn will help us identify defects in cholinergic transmission. [Bennett, 121]

Major causes for Alzheimer's Disease

Amyloid Plaques

There has been enormous amount of research in the field of dementia. Researchers have recently identified one of the important causes for Alzheimer's disease. Autopsy study of the brains of AD patients has revealed the presence of Amyloid plaques between the neurons of the brain. Amyloid and B-Amyloid are two proteins that are synthesized by the body. While in a normal healthy individual these proteins are easily broken down in the case of patients suffering from AD the protein structures seem to…. [read more]


Hmg-Coa Reductase Inhibitors for the Treatment and Prevention of Alzheimer's Disease Research Proposal

… ¶ … Alzheimer's Patients

HMG-CoA reductase inhibitors for the treatment and prevention of Alzheimer's disease

HMG-CoA reductase inhibitors (statins) are rate-limiting enzymes used to prevent cholesterol synthesis. These drugs are used primarily in patients that are at risk for the development of cardiovascular disease. However, recent studies suggest that statins may also be helpful for patients with Alzheimer's Disease. The use of statins in the treatment of Alzheimer's Disease is a new topic, but one that deserves to be considered by future researchers. The following will explore the current body of research concerning the potential benefits of statins for Alzheimer's patients. It will present research plans regarding further exploration of the possibilities that lie in the use of statins in patients with Alzheimer's disease.

Literature…. [read more]


Alzheimers Disease Alzheimer's Disease in Search Term Paper

… Alzheimers Disease

Alzheimer's Disease in search of a cure

The risk for dementia, a major contributor to incapacitation and institutionalization, rises rapidly as we age, doubling every 5 years after age 65. Tens of millions of new Alzheimer's disease (AD) and other dementia cases are projected as elderly populations increase around the world, creating a projected dementia epidemic for which most nations are not prepared. Thus, there is an urgent need for prevention approaches that are safe, effective, and affordable. Much attention has been focused on the abnormal deterioration of the brain called senile dementia of the Alzheimer type (SDAT) which affects five percent of U.S. Adults by age 65 and twenty percent of those over eighty. Diagnosis of SDAT depends on its characteristic symptoms:…. [read more]


Alzheimer's Disease Course Project Part III Term Paper

… Alzheimer's Disease

Course project part III: Describe current initiatives

Environmental

Pre-screening and early intervention in the identification and treatment of AD is essential. One recent NIH-funded study used DNA samples from more than 56,000 study participants and "analyzed shared data sets to detect gene variations that may have subtle effects on the risk for developing Alzheimer's" (Studies find possible new genetic links for Alzheimer's disease, 2011, National Institute on Aging). The study found several new gene variants indicating "risk factors for late-onset Alzheimer's disease, the most common form of the disorder" (Studies find possible new genetic links for Alzheimer's disease, 2011, National Institute on Aging).

This is a form of primary intervention, or preventative treatment. Identifying genes can allow for improved early drug treatment studies…. [read more]


Chemistry Alzheimer's: The Disease Essay

… (Jasmin et al., 2011)

There are a few medications for the treatment of mild to moderate Alzheimer's disease. Physicians prescribe these drugs with the intent of delaying or preventing symptoms from worsening and assisting in controlling some of the behavioral symptoms of Alzheimer's, which can be as difficult as the physical ones. (NIA, 2012) The current medications are: Razadyne, Exelon, Aricept, and Cognex. (NIA, 2012) For the treatment of moderate to severe Alzheimer's, there are medications such as Namenda and N-methyl D-aspartate (NMDA). (NIA, 2012) Each drug has unique side effects and the side effects depend upon the medical history of the patient, the dosages prescribed by the patient's physician, and the patient's reactions to the medication. There are similar characteristics shared among them such…. [read more]


Aricept Alzheimer's Disease Is a Progressive Form Research Paper

… Aricept

Alzheimer's Disease is a progressive form of pre-senile dementia, which similar to senile dementia, except that it usually starts in the 40s or 50s, and with initial symptoms of impaired memory, then impaired thought and speech and, finally, complete helplessness (Lexico Publishing Group LLC 2006). It is a disease in the brain, which makes the sufferer forget how to use a key, walk, talk or eat (Liebman 2002). Recent statistics showed that approximately a third of all people older than 85 have Alzheimer's or another type of dementia. Around 1,000 are diagnosed with it each day in the U.S. And records revealed that the number has been increasing. The projection is that there may be up to 14 million Americans with this disease by…. [read more]

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